Zhao Yufen, female, Han nationality, obtained a doctorate degree from New York State University in the USA. Her primary research fields include life organophosphorus chemistry, biological organic chemistry, organic synthesis chemistry and life origin.
Zhao invented the production method of the new anti-cancer medicine cephalotaxine parent nucleus and developed a series of new non-toxic anti-schistosome compounds. She discovered that the saturated solution of the phosphoramidic acid may incise RNA and DNA. The principle of the incision is similar to that of the hydrolyzing of the phosphodiesterase in biochemistry. Zhao is conducting the research of the nucleic acid fixed-point incising agent by cooperating with Ohio University in the USA.
Zhao also discovered that N - Phosphoramidic acid itself may be developed into polypeptide and turn nucleoside phosphinylidyne into ribotide. Therefore, N - Phosphoramidic acid may simultaneously generate the titanium pool, the nucleic acid pool, and the compound titanium - nucleic acid pool during the same reaction process. In terms of life origin, Zhao discovered that phosphoramidic acid can generate nucleic acid, albumen as well as LB-film and liposome, which is therefore the smallest system of life evolution.
Zhao has taken charge of and completed many major projects of the State Natural Science Fund and science projects of the Outstanding Youth Fund and the Excellent Talents Fund of the State Education Commission, which have won second and third class Science and Technology Advancement Awards of the Chinese Academy of Science, the first China Youth Scientist Award and 2 second class Science and Technology Advancement Awards of the State Education Commission. She has published nearly 200 high quality dissertations in publications both at home and abroad.
Zhao Yufen is a member of the CPPCC National Committee and chairperson of the All-China Youth Federation.