China Vitae

Biography

Jin Guozhang, male, Han nationality, is a native of Yongkang, Zhejiang Province. He graduated from Zhejiang University in 1952.

Jin studied the pharmacological roles of the TCM corydalis tuber and proved l-THP is the main effective ingredient and retarder of the dopamine(DA) receptor. He also proved that l-THP has abirritation and also stabilization properties.

Based on the stabilization of l-THP, Jin inaugurated the research field of THPB's effect on dopamine receptors. He discovered the dual roles of l-SPD, D1 excitation and D2 retardance. This new pharmacological role, coincident with current new argumentation about the pathogeny of schizophrenia (i.e., poor function of pallium prefrontal lobe D1 receptor, while there is hyperfunction of the cortex lower structure's D2 receptor and the first dual-functional stabilizer), led to a new direction for the development of anti-chlorpromazine medicine research. With respect to molecular pharmacological research, Jin proposed a topological diagram that showed that l-SPD and D1 receptors interact. He also proved that dual hydroxide group-THPBs is a type matter with dual-role characteristics. A national invention patent was granted to one of the new compounds.